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What is Active and Passive Targeting

Handbook of Research on Green Synthesis and Applications of Nanomaterials
Active and passive are the two means of targeting nanoparticles. In active targeting, the nanoparticles are actively uptake by the tumor cells while in passive targeting, a location is specified for the nanoparticles in a small place of tumor.
Published in Chapter:
Role of Nanoparticles in Cancer Therapy
Zeeshan Ahmad Bhutta (Chungbuk National University, South Korea), Ayesha Kanwal (The Islamia University of Bahawalpur, Pakistan), Ambreen Ashar (University of Agriculture, Faisalabad, Pakistan), Moazam Ali (University of Agriculture, Faisalabad, Pakistan), Ashar Mahfooz (University of Agriculture, Faisalabad, Pakistan), Muhammad Fakhar-e-Alam Kulyar (Huazhong Agricultural University, China), Muhammad Shoaib (Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Graduate School of the Chinese Academy of Agricultural Sciences, China), Rizwan Ahmed (University of Agriculture, Faisalabad, Pakistan), and Kun Li (Nanjing Agricultural University, China)
DOI: 10.4018/978-1-7998-8936-6.ch016
Abstract
The rapid growth of nanotechnology towards the development of nanomedicines has improved cancer treatment. Nanomedicine provides the opportunity to implement complex and targeted multifunctional strategies. Today, nanoparticles (NPs) have many uses in a number of scientific fields. In recent years, it has been repeatedly reported that NPs hold a significant place in the regulation of modern medicine by implementing a varying number of clinical approaches like drug carrying substances, genetic material delivery to tumors, as well as in radiography as a contrast media agent. Various nanomaterials based on organic, inorganic, lipid or glycan compounds, and synthetic polymers have been used to develop and improve new cancer treatments. In this chapter, the authors discussed the role of NPs in cancer treatment among various anticancer drug delivery methods.
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