Abstract

Wound healing is a complex molecular process that aims to repair the tissue damaged due to the cause of an injury. Chronic and delayed wound healing processes pose significant clinical challenges for the patient. The synthetic drug possesses several side effects when taken for a long time. However, the phytochemicals derived from medicinal plants have gained attention and are eventually used to treat wounds. Due to the large molecular diversity in the phytochemicals, it is difficult to screen the key compound by using traditional experimental methods, as they are expensive and time-consuming in nature. Therefore, computational approaches, particularly molecular docking, provide a better understanding of the mechanisms through which phytochemicals interact with important biological targets involved in wound healing. The mechanistic action of various proteins in the wound-healing process is highlighted in this chapter along with the procedure and implementation of molecular docking studies used to screen potential phytochemicals are discussed.