| ITS | Time | Developer | Main technology | References |
| SCHOLAR | 1970 | Carbonell | Production expert system | (Carbonell, 1970) |
| WHY | 1977 | Stevens, Collins | Stevens and Collins, 1977) |
| SOPHE | 1975 | Burton, Brown | Brown and Burton, 1975) |
| WEST | 1976 | Burton, Brown | Brown and Burton, 1976) |
| BUGGY | 1978 | Burton, Brown | Brown and Burton, 1978) |
| GUIDON | 1979 | Clancey | Clancey, 1979) |
| LISP Tutor | 1985 | Anderson, Boyle, Reiser | Case-based reasoning,
Natural language understanding | (Anderson, Boyle, and Reiser, 1985) |
| Geometry Tutor | 1985 | Anderson, Boyle, Yost | Anderson, Boyle, and Yost, 1985) |
| PROUST | 1986 | Johnson | Johnson, 1986) |
| PIXIE | 1987 | Sleeman | (Sleeman, 1987) |
| Smithtown | 1990 | Shute, Glaser | Intelligent agent,
Natural language understanding,
Neural network | (Shute and Glaser, 1990) |
| Bridge | 1991 | Shute | Shute,1991) |
| Stat Lady | 1993 | Shute, Gawlick-Grendell | (Shute and Gawlick-Grendell, 1993) |
| Sherlock | 1995 | Nichols, Pokorny, Jones, Gott, Alley | Nichols, Pokorny, Jones, Gott, and Alley, 1995) |
| SQL-Tutor | 1996 | Mitrovic | (Mitrovic, 1996) |
| Auto-Tutor | 1997 | Graesser | (Graesser, 1997) |
| VC Prolog Tutor | 2000 | Peylo, Thelen, et al | Intelligent agent,
Grid and distributed computing,
Natural language understanding | (Peylo, Thelen, Rollinger and Gust, 2000) |
| SCoT-DC | 2001 | Herbert, Clark, et al | Clark, Fry, Ginzton, Peters, Pon-Barry, and Thomsen-Gray, 2001) |
| Slide Tutor | 2003 | Crowley, Medvedev | Crowley and Medvedeva, 2006) |
| AHP-Tutor | 2004 | Ishizaka, Lust | (Ishizaka and Lust, 2004) |
| MATHEMA | 2009 | Papadimitriou, Grigoriadou, Gyftodimos | Papadimitriou, Grigoriadou, Gyftodimos, 2009) |
| Mathtutor | 2009 | Aleven, McLaren, Sewall | Aleven, McLaren, Sewall, 2009) |
| IVRT | 2009 | Kim, Wang | Kim and Wang, 2009) |
| Oscar CITS | 2012 | Latham, Crockett, Mclean, | (Latham, Crockett, Mclean, 2012, 2014) |