Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications

Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications

Limin Angela Liu (Shanghai Jiao Tong University, China), Dongqing Wei (Shanghai Jiao Tong University, China), Yixue Li (Shanghai Jiao Tong University, China), and Huimin Lei (Shanghai Jiao Tong University, China)
Indexed In: SCOPUS View 2 More Indices
Release Date: March, 2011|Copyright: © 2011 |Pages: 776
DOI: 10.4018/978-1-60960-491-2
ISBN13: 9781609604912|ISBN10: 1609604911|EISBN13: 9781609604929
Hardcover:
Available
$295.00
TOTAL SAVINGS: $295.00
Benefits
  • Printed-On-Demand (POD)
  • Usually ships one day from order
Hardcover:
Available
$295.00
TOTAL SAVINGS: $295.00
Benefits
  • Printed-On-Demand (POD)
  • Usually ships one day from order
E-Book:
Available
$295.00
TOTAL SAVINGS: $295.00
Benefits
  • Multi-user license (no added fee)
  • Immediate access after purchase
  • No DRM
  • PDF download
E-Book:
Available
$295.00
TOTAL SAVINGS: $295.00
Benefits
  • Immediate access after purchase
  • No DRM
  • PDF download
  • Receive a 10% Discount on eBooks
Hardcover +
E-Book:
Available
$355.00
TOTAL SAVINGS: $355.00
Benefits
  • Printed-On-Demand (POD)
  • Usually ships one day from order
  • Multi-user license (no added fee)
  • Immediate access after purchase
  • No DRM
  • PDF download
Hardcover +
E-Book:
Available
$355.00
TOTAL SAVINGS: $355.00
Benefits
  • Printed-On-Demand (POD)
  • Usually ships one day from order
  • Immediate access after purchase
  • No DRM
  • PDF download
OnDemand:
(Individual Chapters)
Available
$29.50
TOTAL SAVINGS: $29.50
Benefits
  • Purchase individual chapters from this book
  • Immediate PDF download after purchase or access through your personal library
Description & Coverage
Description:

The biological sciences have been among the most exciting and intensely pursued fields of science for the past several decades. The advancement of high-throughput technologies that generate large scale biological data as well as the development of related computational tools has enabled global efforts at understanding complex biological systems and brought revolutionary changes to biological research.

Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications summarizes some of the most recent research carried out in computational biology and systems biology to encourage and guide future study. Submissions to this comprehensive text present methods, tools, and applications developed and considered by many leading experts around the globe.

Coverage:

The many academic areas covered in this publication include, but are not limited to:

  • Biclustering of DNA microarray data
  • Detecting epistasis in genome-wide association studies
  • DNA microarray data
  • Genomic DNA sequence
  • Granger causality
  • Predictive and personalized medicine
  • Privacy considerations for systems biology applications
  • Vaccine Development
  • Virtual Screening
  • Visualization of protein 3d structures
Reviews & Statements

This book, with its well-done illustrations and contributions from leading experts, will be of immense help for novices and researchers interested in this field.

– Omer Iqbal, MD, FACC, FESC, Loyola University Medical Center. Doody's Book Review 2011.

Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications has been developed to summarize and present some of the most recent research carried out in these fields to encourage and guide future research. During the book development process, several hundred world-leading scientists and researchers in computational biology and systems biology were invited to contribute a chapter to the book. Each submitted manuscript was reviewed by at least three reviewers in a double-blind review process. The reviewers may be Editorial Advisory Board members, contributing authors, or external reviewers. From the forty-three submissions, twenty-eight were accepted to appear in the book. The final book is a collection of eighteen thorough reviews and ten original research articles on the state-of-the-art development in the fields of computational biology and systems biology. Methods, tools, and applications of these fields are presented by many leading experts around the globe. The book chapters are written with the objective that novices in these fields will be able to learn the concepts and apply the techniques in their own studies and research. Active researchers in these fields may also appreciate the timely and in-depth review of existing literature and may be inspired to carry out innovative work to move biological sciences forward.

– Limin Angela Liu, Shanghai Jiao Tong University, China; Dongqing Wei, Shanghai Jiao Tong University, China; and Yixue Li, Shanghai Jiao Tong University, China
Table of Contents
Search this Book:
Reset
Editor/Author Biographies
Limin Angela Liu, PhD, obtained her BSc degree from Tsinghua University, Beijing and her PhD degree from Carnegie Mellon University, USA. After postdoctoral research at Johns Hopkins University, USA, she became Associate Professor at Shanghai Jiao Tong University. Her recent work includes the establishment of an ab initio method for the prediction of transcription factor binding sites and a novel “tethered-hopping model” for describing the effects of protein-protein interactions on the formation and stability of ternary protein-DNA complexes.
Dongqing Wei, PhD, is the acting head of the Department of Bioinformatics and Biostatistics, College of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, China, the editor-in-Chief of the journal “Interdisciplinary Sciences - Computational Life Sciences”, and the chairman of the International Association of Scientists in the Interdisciplinary Areas (IASIA). Prof. Wei’s research is in the general area of structural bioinformatics. He is best known for his ground-breaking work on theory of complicated liquids. He, along with Prof. Gren Patey, has found that strongly interacting dipolar spheres can form a ferroelectric nematic phase. This was the first demonstration that dipolar forces alone can create an orientationally ordered liquid state. It is also the first time that the existence of a ferroelectric nematic phase has been established for a model liquid. This discovery solved a long standing problem in theoretical physics, and created a new direction in search for new liquid crystal materials (Phys. Rev. Lett. 68, 2043, 1992, cited about 180 times). In recent years, Prof. Wei has developed tools of molecular simulation and applied them to study biological systems with relevance to computer-aided drug design and structural biology. With more than 150 journal papers and greater than 2000 citations (Science Citation Index), he is becoming a leading figure in the area of structural bioinformatics.
Yixue Li, PhD, was born in Xinjiang, China. Currently, he is the director in Shanghai Center for Bioinformation Technology, vice director and a full research professor of Key Laboratory of Systems Biology at Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. Dr. Li received his BSc. and Msc. degrees in theoretical physics from Xinjiang University, China, in 1982 and 1987, respectively, and his Ph.D. degree in theoretical physics from the University of Heidelberg, Germany, in 1996. After Dr. Li got his Ph.D. degree he worked as a bioinformatics research staff in European Molecular Biology Laboratory (EMBL) from 1997-2000, and came back to Shanghai, China in the middle of 2000. Dr.Li's research interests include bioinformatics, systems biology and computational biology. Dr. Li has published more than 100 journal papers in various international scientific journals, such as Science, Nature Genetics, Nature Biotechnology, PNAS, Bioinformatics, NAR, Plos Computational Biology, Plos One, Molecular Systems Biology, Molecular Cellular Proteomics, Oncogene, BMC Bioinformatics, Genome Biology, etc., and his research results have been cited by more than 1500 researchers worldwide in books, theses, journal and conference papers. Dr. Li has served as an editorial board member for 5 scientific journals.
Huimin Lei, MD, obtained her degree from Inner Mongolia University of Science and Technology, China in 2004. She then became a lecturer and academic advisor for medical students at Baotou Health School,China. Since 2008, she became an Assistant Editor for the journal “Interdisciplinary Sciences – Computational Life Sciences” and an office administrator of Prof. Dongqing Wei’s lab at Shanghai Jiao Tong University. She has served on the organizing committees of several international conferences, including “Theory and Applications of Computational Chemistry – 2008” (TACC2008) and the annual “International Conference on Computational and Systems Biology” (ICCSB) meeting series.
Archiving
All of IGI Global's content is archived via the CLOCKSS and LOCKSS initiative. Additionally, all IGI Global published content is available in IGI Global's InfoSci® platform.
Editorial Advisory Board
  • Tatsuya Akutsu, Kyoto University, Japan
  • Joel Bader, Johns Hopkins University, USA
  • Paola Causin, Universita' degli Studi di Milano, Italy
  • Kun-Mao Chao, National Taiwan University, Taiwan
  • Flávio Codeço Coelho, Gulbenkian Institute of Science, Portugal
  • Pietro Cortona, Propriété et Modélisation des Solides, France
  • Yongsheng Ding, Donghua University, China
  • Todor Dudev, Academia Sinica, Taiwan
  • Andreas Fuerholz, Nestlé Research Center, Switzerland
  • Dietlind Gerloff, University of California, Santa Cruz, USA
  • Haijun Gong, Carnegie Mellon University, USA
  • James A. Holzwarth, Nestlé Research Center, Switzerland
  • Timo Jacob, Universität Ulm, Germany
  • Igor Jurisica, University of Toronto, Canada
  • Yiannis N. Kaznessis, University of Minnesota, USA
  • Samee Ullah Khan, North Dakota State University, USA
  • Jens Lagergren, Stockholm Bioinformatics Center, Sweden
  • Qi Liu, Shanghai Jiao Tong University, China
  • Thomas Manke, Max Planck Institute for Molecular Genetics, Germany
  • Jason McDermott, Pacific Northwest National Laboratory, USA
  • Satoru Miyano, University of Tokyo, Japan
  • Kiran Mukhyala, Genentech, Inc., USA
  • Madhusudan Natarajan, Pfizer Research Technology Center, USA
  • Victoria Petri, Medical College of Wisconsin, USA
  • Piotr Piecuch, Michigan State University, USA
  • Jean-Philip Piquemal, Université Pierre et Marie Curie, France
  • George V. Popescu, University Politehnica of Bucharest, Romania
  • Zimei Rong, Queen Mary University of London, UK
  • Dennis R. Salahub, University of Calgary, Canada
  • Reinhard Schneider, EMBL, Germany
  • Alexander Schoenhuth, University of California at Berkeley, USA
  • Ora Schueler-Furman, Hebrew University, Israel
  • Russell Schwartz, Carnegie Mellon University, USA
  • Temple F. Smith, Boston University, USA
  • Fengzhu Sun, University of Southern California, USA
  • Jerzy Tiuryn, University of Warsaw, Poland
  • Jack Tuszynski, University of Alberta, Canada
  • Esko Ukkonen, University of Helsinki, Finland
  • Lusheng Wang, City University of Hong Kong, Hong Kong
  • Zhuo Wang, Shanghai Jiao Tong University, China
  • Limsoon Wong, National University of Singapore, Singapore
  • Yu (Brandon) Xia, Boston University, USA
  • Zhaolei Zhang, University of Toronto, Canada
  • Deyou Zheng, Albert Einstein College of Medicine of Yeshiva University, USA
  • Xianghong Jasmine Zhou, University of Southern California, USA