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What is Isocenter

Handbook of Research on Trends in the Diagnosis and Treatment of Chronic Conditions
The point in space relative to the treatment machine about which various components of the linear accelerator rotate.
Published in Chapter:
Isocenter Verification in Radiotherapy Clinical Practice Using Virtual Simulation: An Image Registration Approach
George K. Matsopoulos (National Technical University of Athens, Greece), Pantelis A. Asvestas (Technological Educational Institute of Athens, Greece), Vasiliki Markaki (National Technical University of Athens, Greece), Kalliopi Platoni (University of Athens, Greece), and Vasilios Kouloulias (University of Athens, Greece)
DOI: 10.4018/978-1-4666-8828-5.ch010
This chapter presents an overview of the procedures that are used for the verification of the patient position during radiotherapy. Furthermore, a method for the verification of the radiotherapy isocenter prior to treatment delivery is proposed. The method is based on the alignment of two Computed Tomography (CT) scans: a scan, which is acquired for treatment planning, and an additional verification scan, which is acquired prior to the treatment delivery. The proposed method was applied to CT scans, acquired from 20 patients with abdominal tumors and 20 patients with breast/lung cancer. The results of the proposed method were compared with the ones obtained using conventional methods, indicating that the estimated isocenter displacement can be translated into patient setup error inside the treatment room.
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