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What is Factorial Design

Design of Experiments for Chemical, Pharmaceutical, Food, and Industrial Applications
Is one involving two or more factors in a single experiment. The number of levels of each factor and the number of factors classify such designs; is often used by scientists wishing to understand the effect of two or more independent variables upon a single dependent variable.
Published in Chapter:
Optimization of a Spectrophotometric Flow Injection: Method for Determination Copper and Manganese in Wines by Design Experiments
Germán Adán Sánchez Gallegos (Universidad Autónoma de Baja California, México), Maria del Pilar Haro Vazquez (Universidad Autónoma de Baja California, Mexico), José Manuel Cornejo-Bravo (Universidad Autónoma de Baja California, Mexico), and Eugenia Gabriela Carrillo-Cedillo (Universidad Autónoma de Baja California, Mexico)
DOI: 10.4018/978-1-7998-1518-1.ch008
This chapter presents the optimization of the hydrodynamic and chemical parameters of the FIA system in the determination of copper and manganese in wine samples by VIS spectrophotometry. This technique has been based on the injection of liquid samples in the non-segmented movement, within a continuous carrier current of a suitable liquid. The injected sample forms a zone that disperses on its way to a detector. The later continuously records the absorbance or other physical parameters, since it continuously passes the sample material through the flow cell, using the factorial designs Plackett-Burman, Box-Behnken, and the factorial design 2^4. The methods have the advantages of low-cost, easy availability of chemicals, and instrumentation and straightforward application to real samples.
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Design of Experiments in an Electrochemical Process
Experimental design that serves to study the individual effect and interaction of several factors on one or several responses.
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