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What is DNA Microarray

Technological Breakthroughs and Future Business Opportunities in Education, Health, and Outer Space
A collection of microscopic DNA spots attached to a solid surface, which can be used to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome.
Published in Chapter:
Biotechnology: Recent Developments, Emerging Trends, and Implications for Business
Qing-Ping Ma (The University of Nottingham, Ningbo, China)
DOI: 10.4018/978-1-7998-6772-2.ch007
Abstract
Biotechnology utilizes biological systems or living organisms to create, develop, or make products. This chapter reviews the current state of biotechnology and examines its future trends. Currently, biotechnology plays key roles in medicine, agriculture, and industry. In medicine, vaccines which still rely on biological systems for their production, are the best tools to prevent infectious diseases; antibodies and RNA/DNA probes have been crucial in detecting and treating diseases; and genetic editing and gene therapy is making it possible to treat hereditary diseases. In agriculture, biotechnology is generating crops that produce high yields and need fewer inputs, crops that need fewer applications of pesticides, and crops with enhanced nutrition profiles. In industry, biotechnology is being utilized in food processing, metal ore processing, the production of chemicals, and reducing energy consumption and pollution.
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Clustering Techniques for Revealing Gene Expression Patterns
(Commonly known as gene chip, DNA chip, biochip array or high density) A collection of microscopic DNA probes attached to a solid surface such as glass, plastic, or silicon chip forming an array (matrix). Such arrays allow to simultaneously examine the presence of many genes within a DNA sample (which often can also represent the entire genome or transcriptome of an organism). A typical use is to compare the gene expression profile of an individual patient with that of a healthy one to identify which genes are involved in the disease.
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DNA Microarrays: Analysis and Interpretation
Normally a slide made of silica or synthetic materials where on top an ordered array of oligonucleotide clones is imprinted, corresponding to regions of all discovered or putative genes of an organism’s genome, which allows the specific binding of genes or gene products.
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CNS Tumor Prediction Using Gene Expression Data Part I
A collection of microscopic DNA spots, commonly representing single genes, arrayed on a solid surface by covalent attachment to chemically suitable matrices.
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Building Gene Networks by Analyzing Gene Expression Profiles
A DNA microarray (commonly known as gene chip, DNA chip, biochip array or high density) is a collection of microscopic DNA probes attached to a solid surface such as glass, plastic, or silicon chip forming an array (matrix). Such arrays allow to simultaneously examine the presence of many genes within a DNA sample (which often can also represent the entire genome or transcriptome of an organism). A typical use is to compare the gene expression profile of an individual patient with that of a healthy one to identify which genes are involved in the disease.
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Wolf-Swarm Colony for Signature Gene Selection Using Weighted Objective Method
It is the gene expression level of thousand genes collected from different samples in a single microscopic chip.
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Biclustering of DNA Microarray Data: Theory, Evaluation, and Applications
A small solid support, usually a membrane or glass slide, on which sequences of DNA are fixed in an orderly manner. DNA microarrays are used to measure the expression of many genes simultaneously. It is also called DNA chip.
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CNS Tumor Prediction Using Gene Expression Data Part II
Also known as a DNA chip, it is a collection of microscopic DNA spots, commonly representing single genes, arrayed on a solid surface by covalent attachment to chemically suitable matrices.
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High-Dimensional Statistical and Data Mining Techniques
A DNA microarray is the collection of microscopic DNA spots fixed to a solid surface.
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Analysis of Large-Scale OMIC Data Using Self Organizing Maps
A key technology in high-throughput molecular biological data acquisition. They allow massively parallel measurement of abundances of many ten thousands of e.g. mRNAs (expression arrays) or millions of SNPs (SNP array) in a given sample solution.
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